Search on: DNA, SUPERCOILED 
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Descriptor English:   DNA, Superhelical 
Descriptor Spanish:   ADN superhelicoidal 
Descriptor Portuguese:   DNA Super-Helicoidal 
Synonyms English:   DNA, Supercoiled
DNA, Supertwisted
Supercoiled DNA
Superhelical DNA
Supertwisted DNA  
Tree Number:   D13.444.308.283.250
G02.111.570.820.486.212.250
G05.360.580.156.250
Definition English:   Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity. 
Indexing Annotation English:   IM; /drug eff /ultrastruct permitted
History Note English:   78 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22162 
Unique Identifier:   D004278 

Occurrence in VHL:
 

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